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enfermedad compleja Combining multiple genes and environmental factors.
Sinònims
Examples for "complex disease"
Examples for "complex disease"
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Diabetic nephropathy is a common, complex disease with a clear genetic predisposition.
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ACLR is a complex disease with multiple risk factors including genetic predisposition.
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Gene expression variation is an important mechanism underlying susceptibility to complex disease.
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Host genetic susceptibility to adult pulmonary Mycobacterium avium complex disease remains unknown.
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This is a complex disease involving many steps with proper signalling pathways.
1
It is a multifactorial disorder with unclear etiology, affecting predominatly middle-aged women.
2
Obesity is a chronic, complex, multifactorial disorder with increasing prevalence in modern society.
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Cancer is a multifactorial disorder involving multiplicity of interrelated signaling pathways and molecular targets.
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Adolescent idiopathic scoliosis (AIS) is a multifactorial disorder characterized by a tridimensional deformation of the spine.
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Cleft palate most commonly occurs as a sporadic multifactorial disorder with a clear but difficult to define genetic component.
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The potential for genetic screening of multifactorial diseases, for example, cancers, should also be considered.
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In humans, the elucidation of the genetics underlying multifactorial diseases such as pre-eclampsia remains complex.
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Overall genomic discoveries for preterm birth lag behind progress for many other multifactorial diseases and traits.
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The heritability of most common, multifactorial diseases is rather modest and known genetic effects account for a small part of it.
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Unfortunately, the use of these resources and their interpretation are not straightforward when applied to complex, multifactorial diseases such as schizophrenia.
1
Basic tenets of genetic counseling, complex genetic disease, and management of adults with genetic diagnoses also are discussed.
2
T2DM is a complex genetic disease comprised of many metabolic disorders with a common phenotype of glucose intolerance.
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Background: Asthma is a complex genetic disease characterized by reversible intermittent airway obstruction and respiratory symptoms primarily caused by acute and chronic bronchial inflammation.
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Background: Asthma and allergic phenotypes are complex genetic diseases with known linkage to chromosome 5q.
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Future directions, particularly with regard to the study of common complex genetic diseases, are also described.
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This implies value in studying large well-characterized Ashkenazi populations to accelerate gene discovery in complex genetic diseases.
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As with many complex genetic diseases, genome scans for prostate cancer have given conflicting results, often failing to provide replication of previous findings.